Error 160x is normally a result of timeouts
error 1601 may be resolved by disabling, deactivating, or uninstalling third-party security, antivirus, and firewall software.
My suggestion
- Disconnect your PC from Internet. (just to make sure no nasties creep into your system while you syncing.
- Stop the Antivirus program
- Connect your iPod to the PC, using a high speed USB 2.0 port at the back of your PC.
- Disconnect all other USB devices, except the mouse and keyboard.
- Stop all other programs except iTunes.
Good Luck!