Currently Being ModeratedSep 14, 2012 7:16 AM (in response to Santhosh2577)
Enable the "Encrypt iPod/iPhone Backup" option from under the iPod's Summary tab in iTunes.
Remember: iTunes: About iOS backups
Warning: If you encrypt an iPhone backup in iTunes and then forget your password, you will not be able to restore from backup and your data will be unrecoverable. If you forget the password, you can continue to back up and use the device, however you will not be able to restore the encrypted backup to any device without the password. You do not need to enter the password for your backup each time you back up or sync.