Currently Being ModeratedOct 25, 2012 5:47 AM (in response to jm58)
If you do not know the combination, you can try and connect it to the iTunes library you normally sync it. Upon properly ejecting it from iTunes and your PC, you may find that it is now unlocked. If it is, disable the screen lock or change the combination immediately.
Otherwise, your only other option is to connect it to iTunes and restore it to factory settings.