Currently Being ModeratedJan 8, 2013 4:39 PM (in response to Chaz1138)
A MacBook4,1 originally shipped with Leopard, so yes, as long as the disc you have contains the same or later version originally installed.
Any retail copy of OS X can be installed on any system that supports it. Portable or desktop makes no difference.
System-specific discs are grey in color and will install OS X only on the exact same model number Mac that included that disc.MacBooks iMacs iPads AirPorts, OS X Mountain Lion, 28 years Apple!