The only really important numbers are the Page Outs and Swap Used. You are running enough applications (and/or large enough applications) that you need about 3GB of RAM more than your computer has. Since the time you first started the computer your computer has had to move 2.39 GB of data from RAM to the hard drive. If this is normal for your computer use, you could use more RAM.
For more information, read this support article.
You need to Restart your Mac in order to reset the totals to zero. Then if those totals start to climb back up after a short time, you could use a RAM upgrade as dwb suggest's.
For example: my 2010 Mac Mini with 8 GB of RAM has been running for over 2 weeks without a restart, it has 0 Page outs and never shows any sign of slowing down or beachballing.
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