If you are looking to do a complete removal and reinstallation of iTunes, you may find the following article helpful. Note: This may not be an effective resolution to your issue if TuneUp has made changes to any files or settings outside of iTunes.
If you are having network connectivity issues with iTunes (updates, downloads, etc), you may also find the following articles helpful:
Tiffany from TuneUp here So sorry that many of you have had so many issues with TuneUp 3.0. I wanted to let you know that TuneUp is now under new ownership and we have made some MAJOR improvements. You can read more about this transition here: http://www.tuneupmedia.com/com...
To start, we strongly recommend that you download version 2.4.8, which is TuneUp’s strongest, most stable and most accurate version. For more information about how to do that, go here: http://support.tuneupmedia.com...
For those of you interested in checking out TuneUp, please download the free trial. And, if you’re interested in getting the full version, use promo code RELAUNCH14 for 30% off through April 15, 2014.
Again, thanks for your patience and support. Please let us know if you have any questions or comments.