Q: Leaving MacBook Pro at home during 2 week vacation.

Run the battery down to around 50%. Remove it from the computer if it is removable. Store in a cool, dark place.

So like Kappy says that would be the ideal.

Two weeks isn't that long a time:

From:

Mac notebooks: About battery storage life - Apple Support

"Notes on storage

Lithium Ion Batteries (Li-Ion)

• 1 to 2 months - Battery should still have minimal charge to operate the computer
• 6 to 12 months - Battery can still be charged
• 12 months or more - Uncertain

Learn more

Batteries may be damaged if stored for prolonged periods with a closed circuit. The environmental temperature also affects the storage life of any battery. Cool environments are best, and are assumed for the above estimates. All storage times are based on storage starting with the battery fully charged. For example, schools that may not use their Mac notebook computers during a long weekend or break should fully charge the batteries, remove them from the computers, and store them in a cool location for the duration of the break. For computers that have non-removable batteries, shutdown the computer and fully charge the battery. If storage will be longer than a month, fully recharge the battery every two months."

If you're uneasy about opening the computer it would be ok to leave it as noted above.