Q: cursor will not select or move windows

My macbook was getting a little sluggish so quit all programs and restarted. When restarted the cursor will not select text, resize window or move windows. I have reset the pram and the SMC.  Done a disk repair and shut down or restarted many times. Uninstalled 'disconnect me' extension on Safari, logged on to the quest account to see if it was a problem with all accounts, it is. Any other suggestions?  thanks