Q: Cursor is misaligned with Store home page, half of screen unaccessible

Hey there MarcsterSK! 

I'd definitely want iTunes to respond to what my cursor is on when I click it.  We can certainly check a few things. 

If you haven't yet, quit iTunes, restart the computer and try iTunes again, please. If that doesn't change things, let's try iTunes in Safe Mode and also make sure it's on the most recent version. 

iTunes Safe Mode: 

Start iTunes in Safe Mode

When you open iTunes in Safe Mode, you isolate the program from any interference caused by plug-ins or scripts not manufactured by Apple. To start iTunes in safe mode, hold down the Shift and Control keys on your keyboard while you open iTunes.

You'll see a message as iTunes is starting that says "iTunes is running in Safe Mode. Visual plug-ins you have installed have been temporarily disabled."

If the issue doesn't happen in Safe Mode, remove any third-party plug-ins.

Get the latest version of iTunes - Apple Support 

Best wishes!

Hey there MarcsterSK! 

I'd definitely want iTunes to respond to what my cursor is on when I click it.  We can certainly check a few things. 

If you haven't yet, quit iTunes, restart the computer and try iTunes again, please. If that doesn't change things, let's try iTunes in Safe Mode and also make sure it's on the most recent version. 

iTunes Safe Mode: 

Start iTunes in Safe Mode

When you open iTunes in Safe Mode, you isolate the program from any interference caused by plug-ins or scripts not manufactured by Apple. To start iTunes in safe mode, hold down the Shift and Control keys on your keyboard while you open iTunes.

You'll see a message as iTunes is starting that says "iTunes is running in Safe Mode. Visual plug-ins you have installed have been temporarily disabled."

If the issue doesn't happen in Safe Mode, remove any third-party plug-ins.

Get the latest version of iTunes - Apple Support 

Best wishes!