Q: MacPro 2009 suddenly lost sound and startup time is over a minute

I surmise I was not clear with my earlier reply. That Mac is a Petri dish of useless junk, and it simply is not going to work properly. About the only piece of junk thing missing from that Mac is "MacKeeper", which you will also invite if you follow one of the links posted to this Discussion.

I suggest you erase it completely and rebuild it from a Time Machine backup created prior to having burdened it with such ill-conceived things. That is not the only way to recover from having done so, but that's what I would do if it were my Mac. It is also likely to result in the least amount of your time and constant interaction.

I do not make the recommendation to "erase and reinstall" without serious consideration. You really do have too much worthless garbage and equally ill-conceived system modifications to enumerate separately. All those things are unnecessary at best, and scams at worst. They are preventing your Mac from working as designed.

How do you determine what is "garbage" and what is not? Use the following excerpt from Effective defenses against malware and other threats as a partial guide:

Never install any product that claims to "clean up", "speed up", "optimize", "boost" or "accelerate" your Mac; to "wash" it, "tune" it, or to make it "shiny". Those claims are absurd.

• Such products are very aggressively marketed. They are all scams.
• They generally operate on the flawed premise that a Mac accumulates "junk" that needs to be routinely "cleaned out" for optimum performance.
• Trial versions of those programs are successful because they provide the instant gratification of greater free disk space.
• That increased space is the result of irreversible destruction of files, programs, or operating system components normally protected from inadvertent alteration or deletion. The eventual result will be unreliable operation, poor performance and random crashes that may not become evident for months or even years after their use, when updates to programs or OS X are eventually released.
• Memory "cleaners" that circumvent OS X's memory management algorithms work by purging inactive memory contents to mass storage, which can only result in degraded performance and accelerated hardware failure.

Conversely stated: if a software product conveys or enhances the ability to do whatever it is you bought your Mac to do, then it's not "garbage". Creating or listening to music, watching movies, organizing your documents, developing work products, communicating with text messages or email, playing games and otherwise entertaining yourself are a few of the reasons Apple designed the Mac. They designed it specifically to preclude the need for non-Apple "anti-virus", "maintenance", "cleaning", "protection" or "enhancement" utilities. Those things are scams with one and only one true purpose: to exploit Mac users and take their money – regardless of whether they are "free" or not.

Not having Anti-Virus software is not living on the edge, there are no viruses that target Mac OS X.

Have a good look through your Apps and see which ones you can live without, you seem to have a lot of the same type of apps doing the same thing, update any if they have versions for Yosemite.

You also have a lot of login items, do you really need all those apps opening up when you power up.