Machine mistakenly thinks mouse button is held down while dragging

I have a bizarre, intermittent problem. Very occasionally, when I'm dragging files between folders, my computer thinks that the mouse button is still being held down even after I release it. As a result, I am constantly "carrying" the files around the screen with the mouse and I'm completely incapable of doing anything else since the machine thinks I'm mid-drag. As far as I can figure out, the only way to fix this is to reboot the machine. Extreme, I know, but I can't figure out any other way to get out of this state. This typically happens to me once or twice a week and I use my computer fairly heavily.

So, has anyone else heard reports of this bizarre behavior before? Any solutions?

I don't know if this matters, but I'm using a wireless mouse. However, plugging in a wired mouse while this is happening doesn't seem to be a solution.