Yes, you can delete them.
I don't use any anti-virus software, but I don't agree that anti-virus software necessarily causes any problems. Many people use and are happy with ClamXav, Norton Anti-Virus, McAfee, etc. I think you just have to understand the state of malware on the Mac and how to handle things. Currently there are no viruses that affect OS X, but there are a few worms and trojans. You should be careful about what sites you visit, what files you download, etc. You should be vigilant, but not paranoid, and also not complacent.
The internet is a dangerous place, but you're safer using a Mac than you would be using Windows (note I said 'safer', not 'safe'). Use the amount of caution/anti-virus that you're comfortable with. Eventually, somebody is going to write a virus that affects OS X and we'll all have to get anti-virus software.