Some routers let you spoof a MAC address: this is useful if your ISP (usually when it's cable) will only accept one MAC address, so you set the router to the address of one of your computers (so that you can bypass the router if necessary). However in the computers themselves the MAC address is set in hardware and is not changeable (which is the point - every device, ethernet card, wificard, router, standalone internet radio, has its own identifiable MAC address.