I have a mid-2007 2.16 Core2Duo with 4GB of RAM and I think COD2 runs fine. What were you running it on before, or are you just buying it now? I also have a G5 dual 1.8 with a 64MB nVidia 5200 card, 1.25 GB RAM, and a Samsung 22" monitor and I think while the MacBook doesn't look as good as the G5, it does a more than adequate job. If you had a powerful tower with a good video card before you will notice a difference (for the worse) but if this is your first use on the MacBook you will be OK. I do have 4 GB in my MacBook. With your Santa Rosa you should be fine. My version of COD2 is PPC not Universal Binary for Intel, so it is running in Rosetta emulated on the MacBook. I don't know if COD2 has been made into the Intel version yet. If it has, you are in even better shape.