phpMyAdmin is great, but did you know about "MySQL Administrator" and "MySQL QueryBrowser"? They might be more your speed.
<http://dev.mysql.com/downloads/administrator/index.html>
<http://dev.mysql.com/downloads/query-browser/1.1.html>
These are Mac apps (also available for Windows & Linux) that provide GUI to MySQL administration and querying. You launch them just like you would Microsoft Word. You can use them to access DBs remotely or locally, so if you install them on your work computer, for example, you can use them to access your home computer.
You won't have to worry about phpMyAdmin's or Apache's configuration files, and you won't be introducing new security holes to your systems (avoidable with phpMyAdmin, but not straight forward to mere mortals). Of course, phpMyAdmin provides remote access to your databases from any computer with a web browser -- Administrator and Query-Browser won't do that.