There is a bluetooth config menu in your Lexus - both the incoming and outgoing audio can be adjusted.
Get in your car with the engine off, the doors closed and the windows rolled up and turn the electrics on, then...
1. make sure you are on the nav screen
2. turn the headlights control to off and WHILE HOLDING DOWN THE INFO BUTTON
3. turn the parking lights on (one click up from headlight off)
4. turn the headlights control to off
5. turn the parking lights on (one click up from headlight off)
6. turn the headlights control to off
7. turn the parking lights on (one click up from headlight off)
8. turn the headlights control to off
That gets you into the config menu - pick the bluetooth option and play away.
Hold down DISPLAY for 5 secs to exit the menu when you are done
While you are in the config menu you are not connected, so each time you change a setting you will have to exit to make a test call.
Default setting is 00, I found that my connection issues went away on 03, but I have also had 2 iPhones and each one worked better on a different setting...
Hope that helps...