Heres what Lacie advises in case anyone else runs into this problem:
Thank you for contacting LaCie Technical Support.
We are sorry to hear you are experiencing problems with your LaCie product.
What's going on with the drive physically? Can you feel/hear the drive spinning inside? Is the case vibrating slightly? Is the light on the front of the drive blinking, solid or off? What about the light on the power adapter? Is the power adapter hot?
Hopefully the issue of the drive not mounting can be cleared up once we understand what the symptoms are.
First, make sure the drive is connected properly and powered on. Open up the Apple System Profiler and look at the Devices and Volumes tab (OS 10.1.x-10.2.8) or select the Firewire/USB bus on the left (OS 10.3). On the Firewire/USB bus, you should see the LaCie drive showing.
If not, start by opening the Disk Utility and running Permissions Repair on the boot drive (OS 10.2 and newer). Reboot and check for the drive again in the Apple System Profiler: if it still doesn't show, try a different cable, try different ports, etc. and refreshing the display (Apple-R).
Please try the drive with a different power adapter from another LaCie drive (with the same power specifications). If you do not have a second power supply to try or find the power adapter is the problem, we can request a replacement power supply be shipped to you. If the drive is a mobile drive with USB try plugging in the power sharing adapter cable in first and then the data cable.
If the drive still refuses to show, uncable it from the Firewire/USB and the power and allow it to rest overnight before trying one more time. Verify that the Firewire/USB ports on the computer are still functional. If you do not have another device to test, remove all cables (and batteries if a laptop) from the computer and allow it to stand overnight as well.
Once the drive is showing on the Firewire/USB bus, it should be mounting. If not, you may be receiving an error message to the effect that the volume is not readable and the computer wishes to reformat. If you get that message, the computer and drive are talking but the format on the drive has been corrupted and the OS can no longer mount the drive.
Open the Disk Utility and run First Aid on the drive. If Disk First Aid cannot repair the drive, there are a few third-party disk utilities you can try. The best is Data Rescue (www.prosofteng.com/lacie) which will scavenge for requested files and copy them to a different volume. It doesn't make any changes to the drive at all, so if it fails, a professional data recovery service can still easily retrieve the data. Should you require professional data recovery, we recommend DriveSavers at 800-440-1904.
If you do not need the data back, or have retrieved what you wanted, you should reformat the drive using Apple's Disk Utility in OS X.
Disk Utility Formatting in OS X (will erase the drive)
Click on Go
Choose Application
Choose Utility
Choose Disk Utility Highlight the Drive you want to format (choose the top line that represents that drive not the indented line that is the volume)
Click on Partition tab (not available at volume level)
Click on OS9 drivers (if you will be using drive on an OS9 machine)
Choose how many partitions
Choose the format you want to use such as Mac OS Extended Click on Partition.
Please let us know the results of these troubleshooting recommendations. Be sure to provide us with specifics as to what you've tried and what the results were.
We hope this helps you in some way. If not, we appreciate your feedback and look forward to resolving this issue with you quickly and correctly. If you have any additional information you feel may help us troubleshoot this issue more efficiently, please let us know.