RIM BlackBerry released a Mac version of their sync software on September 3.
I've begun using it to replace Missing Sync version 1. I never got Missing Sync version 2 to sync, so I downgraded to version 1.
So far, BlackBerry's Desktop Manager is working well. It will even update your BlackBerry's OS, which PocketMac and Missing Sync cannot do and was previously impossible without using Windows. It is compatible with Leopard and Snow Leopard.
This article describes the application and provides a link to BlackBerry's Desktop Manager at the bottom:
http://www.sfgate.com/cgi-bin/article.cgi?f=/g/a/2009/09/03/urnidgns002570F30059 78D885257626006594E9.DTL
By the way, the OS update took a long time. I've heard that that's typical. During the process, Desktop Manager saved my BlackBerry's data and applications. It reinstalled all the apps, including the 3rd party stuff.