iTunes won't open, even after complete uninstall/reinstall of iTunes/Qktime

You might try deleting the iTunes preference files (the ones in your user Library -> Preferences folder) and see if that helps.

I am having the same problem, all the sudden itunes stopped working. Tried systematically deleting preferences from several places, still no luck. Reinstalled itunes, same message. Now backed up, uninstalling completely, then reinstall. This is incredibly frustrating.

krlecarp, you'll be more likely to get a quick and accurate answer if you ask in the Using iTunes for Windows forum. The proposed solutions for a Mac version will quite likely be different than those for a Windows system.

Regards.

Update... so i backed up files from three folders shown below:

'User'/AppData/Roaming/Apple Computer/
'User'/AppData/Local/Apple Computer/
'User'/Music/iTunes/(all files except music and app folders)

Then I uninstalled iTunes & Quicktime
Restarted Machine
Reinstalled iTunes (which reinstalls Quicktime as well)
Opend iTunes to make sure it worked (it did), then closed it.
Copied all of the original files back over to their original locations.
Restarted iTunes
Everything appears to be back to normal (iPhone sync works properly as well)

Hope this helps for anyone else seeking an answer!

Kyle

Thanks, but this would be of more help in the iTunes for Windows forum. Your advice won't apply to a Mac.

This has work for some. Try removing the Genius database. In the "Finder" go to the /username/Music/iTunes/ folder and delete the "iTunes Library Genius.itdb" file. This may allow the program to launch again. This file will be recreated upon first use of the "Genius" feature.