Hi,
as far as i know, the Edirol has a switch on it's back to select between standard and advanced drivers. Standard should work with Core Audio Standard (without drivers), but to use "Advanced" you need the newest Roland driver.
The buzzing can have other causes. Please make shure you put your speaker's power cord into the same power outlet source as your iMac and (if it has) the edirol power connector. Check if none of the cables is lying beneath a power cable, transformer or whatever could induce humming.
But: If the problem persists, and you just bought the Edirol, turn it back to the dealer - it may be a defect (this may happen even with edirol 😉 )
Fox