iWeb window won't load - and all menu options are greyed-out

Hi, I had the same problem!
After one evening of pulling my hair out, I tried the following:
1. Located the 'domain' file (or package). In my case at /*user/Library/Application Support/iWeb.
2. moved the domain file to the desktop (or somewhere else)
3. Started iWeb. I got the warning that iWeb needed a domain file in order to operate, and I confirmed that I wanted the program to create a new one for me.
4. iWeb started as normal, but with no contents. I closed iWeb.
5. I ctrl-clicked the original domain file on my desktop, and selected 'show package contents'.
6. I ctrl-clicked the new, empty domain file in the Application Support/iWeb directory, and selected 'show package contents'.
7. I deleted everything in the new, empty domain package file.
8. And finally copied the contents from the old (seemingly corrupt) package file into the new one.
9. Hooooray! iWeb started with the old contents intact!

Tom… I had exactly the same problem and I followed your method exactly. Works GREAT!!!!!! You saved my websites!!!!!!!!! Yippee!

Tom, thank you for the quick fix! My 19 sites are saved and so is my sanity. Same problem...No Windows on opening iWeb 09. Solved in no time with this solution.
Thank you-desmal