Yes- Colin Jeukens posted step by step instructions back a couple of months ago. Here it is again...
Out of the box the mini comes without Raid. You have two identical HDs of 500Gb.
I have just set it up as Raid1. You can't do this when you use the startup disk from the mini. And as you don't have a Superdrive ... you need to be creative. You need another Mac with Firewire.
Step 1: Start the Mini in Target Mode. Press the T during start. In a few seconds the firewire logo will appear on your screen.
Step 2: Go to your second Mac. Connect the firewire cable between second Mac and Mini.
Step 3: On the second Mac start the disc utility. The two identical drives on your mini will show. Create a new Raid set (mirrored = Raid 1). Include both drives. Confirm the warning that all data on the mini will be lost.
Step 4: Make sure your second Mac has CD/ DVD sharing option installed. This is tou use the superdrive to install OS X Server on the mini.
Step 5: Shutdown both Macs
Step 6: Start your second Mac in target mode. Make sure the firewire cable is still connected.
Step 7: Start the Mini with the option key pressed.
Step 8: Insert the OS X Server install disc in your second Mac.
Step 9: wait till the drive logo apears om the Mini. Continue the install. Will take about an hour.
Here is a link to the original post...
http://discussions.apple.com/thread.jspa?threadID=2213470&tstart=0