Generally just dragging the app and/or folder to the trash will delete the app and any supporting files. There may also be some files left in one of the library folders. An application like AppZapper will search your system and delete all the files related to that app.
I have noted an excerpt from Adobe, regarding uninstalling Photoshop CS4, for you to check out.
+In Mac OS DO NOT drag applications to the trash to uninstall them. To safely uninstall on Mac OS X, double-click the product installer in Applications/Utilities/Adobe Installers or double-click on the Uninstall alias located in the Application folder. Authenticate as an administrator, then select Remove Components and follow the on-screen instructions.+
LukeD beat me to it...with major applications, always be suspicious of the "drag to trash" method. That's usually only right with small apps. With major apps you should always check if there is an uninstaller you should be using. Major apps tend to leave large collections of files in several places which you will miss if you just drag one icon to the trash, this includes sprawling Apple apps like Final Cut Pro. Adobe apps also have online activation of their licenses which you should be sure to deactivate first, like you do with iTunes.
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Deleting Photoshop CS4 from a MacBook Pro?
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