I have the same problem with the Presonus Firestudio Project and Snow Leopard. I'll download the beta drivers from Presonus's web site, uninstall the old drivers, install the new ones, and I can usually get the Presonus Firestudio Project to work -- briefly. Then maybe a day later, there's no sound, and usually the device isn't being recognized. So I'll repeat the whole uninstall, reinstall process, and the box will work and I can return to my projects in Logic, etc. -- for, typically, another few hours. It's now been more than 7 months since Apple released Snow Leopard, and Presonus still has nothing other than an unstable beta driver that is essentially nonfunctional? That's ridiculous. I could understand if this was an old, legacy product, but this thing is still being sold. If I want to keep making music on a Mac, I don't see any options other than to write off my $500 investment in the Presonus product, dump it in the trash, and shop for a new interface from another company. Can anyone recommend a Firewire interface in the $400-$800 range -- from manufacturer that is committed to, and has consistently supported, the Mac platform with updated drivers?