Another me too. In particular the symptoms are this:
+ any YouTube video embedded within a webpage loads the poster frame and the controls, but after clicking the play button only shows the progress indicator briefly before showing "An error occurred, please try again later." within the video frame.
+ the same YouTube videos play fine on the YouTube site.
+ other Internet video plays fine, embedded or not.
+ when the error occurs Safari reports "One error in opening the page. For more information, choose Window > Activity".
+ the Activity window shows "forbidden" for
http://v13.lscache4.c.youtube.com/videoplayback?ip=0.0.0.0&sparams=id%2Cexpire%2 Cip%2Cipbits%2Citag%2Calgorithm%2Cburst%2Cfactor%2Coc%3AU0dWSVhMVV9FSkNNNl9QRllH &fexp=900028&algorithm=throttle-factor&itag=34&ipbits=0&burst=40&sver=3&expire=1 274817600&key=yt1&signature=C15947474FA80C9A1B9DA597103C5FF7D621A478.0C1490DE456 5D519F602B0043A4E1F9D800417A0&factor=1.25&id=c3e8886e8b459334
+ the same URL downloads fine when visiting YouTube directly, except the signature value is different.
I have tested the following:
+ the same computer worked fine a week or so ago
+ other computers on the same shared ADSL connection work fine
+ Firefox works fine (contrary to other's experiences)
+ deleting com.apple.Safari.plist doesn't help
+ disabling/enabling the "Enable Plug-ins" preference doesn't help
+ deleting Preferences/Macromedia folder doesn't help
+ reinstalling Flash doesn't help
+ empty cache doesn't help
Tis quite perplexing.