Hi Mads Meskalin,
got the same combination here.
Content creation in Motion/FinalCut and intuitive graphic works in Modul8.
Not for VJing but for motion grafix.
I choosed M8 years ago cause of it's broadcast quality under realtime circumstances ...
(Mads, you know what I mean ;-))
For your "alpha needs" I indeed recommend
Apple's ProRes 4444 or
Bitjazz's Sheervideo (which costs!)
Sheer has a couple of lossless codecs (e.g. 4224 derivates)
that do not load too much the cpu cause its lossless/uncompressed.
But, - compared to animation or other highend codecs Sheer runs like butter.
It's like scrubbing through a dv-pal movie.
And it plays realtime over long time.
No frame dropping after 30sec (as often seen with animation...)
An additional plus for this Codec-Family is: It has a excellent behavior over generations.
So, for my work I use both families in the mix.
You should try the trial.
Peter at
http://tv.empd.info