FWIW - I'm running into the same thing with apps quitting mid-stream. I'm running into this in EverNote, HoursTracker, WebEx, and a couple other apps. Email is VERY slow to update too.
As a test, I disconnected my iPad1 from my work network, and everything seemed to be stable again. I then reconnected to the network and the App instability returned. Last evening, I tried the same test with my home wifi. The apps would abort when connected, but were stable when wifi was turned off.
I'm no "tech weenie", but it seems that there's an issue with the wifi part in iOS 5.0.1 (version my ipad is running - and I updated Monday).
I'll try the wipe and restore when I get a chance. I'm keeping my fingers crossed.