How can I remove a file in Activity Monitor?

OK, your explanation helped clarify a lot - thanks.

First of all, what Activity Monitor shows in its leftmost column are process names. A process is something that is running on your Mac. Processes use CPU, memory, and usually other resources. In your case, you are seeing network is being used as well.

Your assumption about being associated with a previous "Flip" camera sounds completely reasonable. So if correct (likely), then there would be one or more "Flip" applications likely residing in your Applications folder that you no longer need. You should remove the application. Here is how. Likely the "Finder" method will be easier for you.

How to delete apps on your Mac - Apple Support

torchlite wrote:

flipshareautorun is listed in both Memory and Network within Activity Monitor. I am running Mojave, OS 10.14.4. Any suggestions as to how to get rid of it?

Activity Monitor is not the place.

But look for the following:

/Library/Application Support/Flip Video/FlipShare Uninstaller.app

/Library/LaunchAgents/com.flipvideo.FlipShare.AutoRun.plist

/Library/LaunchDaemons/com.flipvideo.FlipShareServer.launchd.plist

also for parts and pieces:

in your login items >System Preferences>Users&Groups.

as well as:

~/Library/LaunchAgents

/Library/LaunchAgents

/Library/LaunchDaemons

/Library/StartupItems

Once removed, reboot.

Reboot.

flipshareautorun

You can search for and remove any flipshareautorun files you may find by downloading and searching with Find Any File. You'd do the following search: 

Name contains flipshareautorun 

Any files that are found can be dragged from the search results window to the Desktop or Trash Bin for deletion.

FAF can search areas that Spotlight can't like invisible folders, system folders and packages.

Your question makes no sense. Here are some of the reasons:

• Your post's header asks about removing a file. What makes you think flipshareautorun is a file?
• What would prompt you to want to remove this - among all the other items listed?
• Unless this is some application you installed that you no longer wish to keep, or some file you're specifically knowledgeable about, why would you be trying to tamper with the inner workings of your operating system?

And by the way, the current version of MacOS Mojave is 10.14.5.