If you haven't pre-ordered yet, your chances are slim to none at this point. Millions upon Millions are in line ahead of you and Apple is going deliver to those who pre-ordered ahead of you.
If you need an in-store pickup and that option is not showing in the Pre-order options, it means it's not an option available to you.
Your only other choice at this point is to get up very early and visit your closest Apple Store before they even open. If you want to try for launch day. It would be smart to get inline in the hours before the sun rises as lot's of people will line up that day in the hopes they are one of the lucky few who can get a phone without a reservation. Apple will stock some limited supplies, but it's limited at best.
If you read what's happened with sales of the new phones it's being reported they are outselling forecasts by a high margin. Meaning, demand this year is quite high.