You must first cancel any subscription automatic renewal (if you simply delete an app this does not cancel subscriptions):
View, change, or cancel your subscriptions [subscription automatic renewal] - "Your membership or subscription might renew if you don't cancel your membership or subscription more than 24 hours before your renewal date." At this stage the renewal is considered a purchase. Canceling a subscription does not automatically start a refund since the existing subscription will normally continue until the end of its term and then just not renew. - https://support.apple.com/HT202039
If you wish a refund: Apple's terms of purchase in the USA are, "All Transactions are final" (https://www.apple.com/legal/internet-services/itunes/us/terms.html), but some countries have different laws so check terms for your country at: http://www.apple.com/legal/internet-services/itunes/. If sales are final then it is Apple's decision if they want to grant a refund. You can always ask, and people do get refunds on a case by case basis, but Apple can also say no.
For a subscription refund you will have to make a special request using one of the contact links below.
Contact iTunes Support:
https://www.apple.com/emea/support/itunes/contact.html
https://support.apple.com/country-selector/itunes