Removing residual crap from System Info

Select one of those entries. Its Location will be revealed in the lower part of that window—a part you did not capture.

You can select that location (select the entire path) then secondary-click to reveal a contextual menu. Selecting Show in Finder will open a Finder window containing it. You can dispose of it from there in the usual manner.

Yes, I know you want to remove them, I was just first trying to fix the problem.

If you'd still rather remove them, Wacom has its own uninstall tool. First reinstall the drivers so you can proceed from within the app to remove everything.

Then follow the instructions here.

The drivers work just fine in Catalina if you do what the OS says and allow it system access.

If you want to use your tablet, reinstall the latest drivers from Wacom. Open the System Preferences and click on Security & Privacy. Click on the Privacy tab. Click on the lock at the lower left and enter your admin password.

Generally, everything the drivers need access to are already listed under Accessibility and Input Monitoring. You just need to turn the check boxes on next to each. That tells the OS you consider them okay and it will stop asking. Restart the Mac after turning these on.

No problem, I do understand where you're coming from.

I installed the latest Wacom drivers in Catalina and followed the prompts to okay them in the System Preferences. Restarted and the OS complained again. Went back to the System Preferences and found some of the check boxes had gone back off on their own. Turned them back on. I had to keep doing this in order to use the tablet after each restart or startup.

Thought that also is exactly what you described. I had first installed the version I had, which was current at the time. Then about a week later, Wacom released a Catalina specific update. Problem solved. Turn on the check boxes and the stay on with the first try.