trying to open 64bit Wine application on a MacBook Pro 16. There is no open anyway option in system preferences. How can I proceed?

Control (right) - click on the app and select Open from the contextual menu. You'll then be presented with another window where you can open cancel or move it to the Trash.

Maybe you could describe exactly what the problem is? What do you mean by "no open anyway option?" What error message do you get when trying to run Wine?

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Thank you for your understanding and support.

Start from the beginning: did you already install Wine, and did you confirm it's actually working?

The obvious reason for asking is that you won't be able to open a Wine app until then.

Some moral education from the non-tax paying, chronically over-charging apple would be hilarious.

Check your sources before demonstrating your ignorance. Apple is by far the world's largest taxpayer.