1. Remove Adware.
Run the latest release of Malwarebytes for Mac to remove malware/adware, if installed on your Mac.
For instructions: Install Malwarebytes for Mac v4 Uninstall Malwarebytes for Mac
Click the “Scan Now” button. Once done, quit Malwarebytes for Mac.
Restart the computer and relaunch Safari holding the shift key down.
Repeat the scan couple of times.
2. Additional steps to take if necessary.
1. Remove unknown extensions: Safari > Preferences > Extensions
https://support.apple.com/guide/safari/use-safari-extensions-sfri32508/mac
2. Reset search engine: https://support.apple.com/guide/safari/customize-your-search-ibrwe75c2a3c/mac
3. Reset Homepage. https://support.apple.com/guide/safari/set-your-homepage-ibrw1020/mac
4. Restart your Mac. Relaunch Safari holding the Shift key down.