Catalina, iMac late 2015, restarting and showing prohibited after sleep

Failed. Machine started displaying the prohibited sign again after a couple of hours. In essence my takeaway is that even if you upgrade from El Capitan to Catalina or complete a fresh install of Catalina you run into trouble.

I've reinstalled El Capitan and upgraded to Mojave and all is working perfectly proving that this isn't a hardware issue. There are no reported errors in Disk Utility and the machine is running perfectly. I'm slightly annoyed at the amount of time I have spent on this and clearly there are issues running Catalina on my iMac and I'm pretty confident this is an incompatibility with the fusion drive.

If anyone is interested here is the specification of my storage and hard disk.

Intel 10 Series Chipset:

  Vendor:                              Intel

  Product:                             10 Series Chipset

  Link Speed:                        6 Gigabit

  Negotiated Link Speed:    3 Gigabit

  Physical Interconnect:      SATA

  Description:                       AHCI Version 1.31 Supported

APPLE HDD ST1000DM003:

  Capacity:                                 1 TB (1,000,204,886,016 bytes)

  Model:                                      APPLE HDD ST1000DM003          

  Revision:                                  AQ03   

  Serial Number:                        W4Y6SF29

  Native Command Queuing:   Yes

  Queue Depth:                          32

  Removable Media:                  No

  Detachable Drive:                   No

  BSD Name:                             disk1

  Rotational Rate:                      7200

  Medium Type:                         Rotational

  Partition Map Type:                GPT (GUID Partition Table)

  SMART status:                        Verified

  Volumes:

EFI:

  Capacity:           209.7 MB (209,715,200 bytes)

  File System:      MS-DOS FAT32

  BSD Name:       disk1s1

  Content:            EFI

  Volume UUID:   0E239BC6-F960-3107-89CF-1C97F78BB46B

disk1s2:

  Capacity:       1 TB (999,995,129,856 bytes)

  BSD Name:   disk1s2

  Content:        Apple_APFS

Macintosh HD:

 Available:                 912.08 GB (912,084,684,800 bytes)

 Capacity:                  1.02 TB (1,023,683,072,000 bytes)

 Mount Point:            /

 File System:             APFS

 Writable:                   Yes

 Ignore Ownership:   No

 BSD Name:              disk2s1

 Volume UUID:          93AD19AE-A211-34D3-991A-CAB7887D8C03

 Physical Drive:

 Device Name:            APPLE HDD ST1000DM003

 Media Name:             AppleAPFSMedia

 Medium Type:           SSD

 Protocol:                    PCI-Express

 Internal:                      Yes

 Partition Map Type:  Unknown

I just thought I could try reseting the Fusion drive:

1. CMD + R = Disk Util show MT errors on Disk (Volumes were error free)
2. Command Line = diskutil resetFusion
3. Disk Util now show no error on Disk
4. Reinstall Catalina from recovery partition

Hopefully this might resolve the issue?

Quick update:

Completed the fusion drive reset.

Disk util showed the drive, container and volumes as OK

Minutes later the container showed 4 warning: MT mapping (...) is not completely referenced.

So far the machine has restarted to the prohibited sign but I'll continue to monitor. I've noticed other threads talk about a possible issue with Catalina and Fusion Drives?