Reading Speed of HFS+ vs exFAT

Hi,

I have iMac Pro with installed Mojave and window 10. I want to use my HDD (USB 3, 4GB with 7200rpm) as file storage for my VST sample libraries. The DAW hosts ( Cubase) need to READ the samples very fast off of the HDD. I was wondering does it make a difference in terms of the speed using exFAT?

If it is significantly slower, I need to consider buying another HDD and clone it in the other one.

Any help would be greatly appreciated.

CS