Not sure about the iPhone4 version of the Otterbox Defender... but I had the Defender for both the 3GS and an iPod touch. In the 3GS case, the lens is "open" as in unobstructed, so the camera still works. But there is a layer of clear-plastic incorporated in the case, which covers the screen, the camera-lens, and the apple logo. So those are all visible, but still covered and protected from scratches. The Defender case is great - undoubtedly the toughest case made. If you're in construction, or using your iPhone outside a lot, it's a must.