Setting default font for Preview

No. The font that was used to create the PDF originally can't be changed. It's part of the file itself.

dennyup Said:

"Setting default font for Preview: Is there a way to change the default font for documents opened with Preview?"

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Recommend this to Apple:

Recommend this to Apple. The more feedback Apple received on this, the more likely they will consider making a fix.

Where and How to Officially Report this Bug:

1. Go Here: Feedback - macOS - Apple
2. Select: "Feature Request" for the "Feedback Type"
3. Select: "Applications/Utilities" for the "Feedback Area"
4. Proceed from there as necessary

It's not a "Bug".

dialabrain Said:

"It's not a 'Bug'."

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You're Correct. It's feedback:

Where and How to Officially Report this Feedback:

Feedback is not necessary. Read Old Toad's post. There's no such thing as changing the default font for PDFs.