Hello and thank you for your quick response.
This behavior appears to be app agnostic, meaning it occurs to different apps (apple or 3rd party) at different times. With the exception of Messages, I expand my apps windows to consume the entire monitor (but not full screen view) so that I still have the apps bar at the bottom displayed. The problem appears to occur only with apps in my expanded view, i.e., Messages always appears centered where I place it. I've confirmed this performing multiple normal "Restart" and "Shut Down/Start".
Upon one "Restart" I also noticed that the desktop image was also misaligned, up and to the left. This created a behavior where the mouse would not right or down in any application beyond the right and bottom borders of the desktop image. A "Shut Down/Start" corrected this behavior.
Trying your suggestion to start in Safe Mode, I shut down the Mac, I pressed and held the power button for 10 seconds but the startup options window did not display and the Mac powered off as if I performed a forced shut down. I tried this multiple times with the same result. I did notice that the Apple logo appeared after ~5 seconds and then went dark at ~8 seconds followed by aforementioned power off. So I cannot complete this test as proposed.
Any next thoughts? Thanks.
