I can not access my iCloud because I don’t have the number anymore

Then you will need account recovery -- Two-factor authentication for Apple ID - Apple Support.

"If I can't sign in, how do I regain access to my account?

If you can’t sign in, access a trusted device, reset your password, or receive verification codes, you can request account recovery to regain access to your account."

Hi - you can always recover your Apple ID password with several options. There is no need to have your old phone number. Please take a look and try some of the suggestions in the attached article: https://support.apple.com/en-us/HT201487

If these don't work, you can call Apple Support. They will help you to recover your password.