Can I use HomePod with two different iPhones?

Yes, the scenario is myself and my wife in our home sharing a single HomePod. We have separate Apple Ids. I have it set up now where my wife and i share the HomePod. I invited her to My Home. That works fine. The somewhat confusing part is the "Home" on the Home app on my wife's iphone Home app shows up as "My Home (Guest)" and another home called "My Home" that shows her as the primary person. OK, not a problem, but still clunky. Next i will have the HomePod recognize her voice and i will report on that in a separate post.

The HomePod recognizes both my (primary) voice and my wife's voice. I caution others that all the various settings that need to be checked or set are across multiple apps (iPhone settings, Home settings, and in our case Pandora settings) and between two different iPhones are numerous. Its not a simple setup procedure. And ultimately, my wife's Home app shows a 'default' Home with no devices, and a Home (guest) which i presume is the shared home with our HomePod as a device. It all works, but my wife wants to know why i have a home and she is a guest in my home. :-)