Since it works when in Safe Mode that means that something not loaded in Safe Mode is causing the problem.
Download and run this app.
https://etrecheck.com/upgradeIt shows what is launched and other information and is very useful in finding causes of problems. After you first launch the app make sure you check Enable full disk access in the box in lower left.
After running the app use the app's feature to paste to clipboard. The in the text box for a reply in this forum click on the addition text icon. This is because the normal reply text box limits how much you can type.
No personal identifiable information is contained if the app output. The app was written for a person who is contributor to these Apple Support Communities
Have you checked Lacie's support site for any firmware oe software update?