Thank you for the Etrecheck Report
Please refer to below as several pieces of Software maybe the Root Cause >>
MacBook Pro (16-inch, 2019)
macOS Big Sur 11.6.2 (20G314)
Q 1 - Antivirus software: Apple and ESET
A 1 - ESET would not run in Safe Boot as Safe Boot would eliminate it from loading.
Further, there are no known Windows-like Viruses in the wild that self replicate and affect macOS, because of the underling UNIX Foundation and Permission Limitation.
- The Only thing this software is protecting is the Bank Account of the Developers with Zero return to the user ( you ) for a Non Exiting issue affectioning macOS. Remove as per Developers Specific Instructions.
The The Built in Security is all that is required to protect the computer.
Q 2 - Launchd: ~/Library/LaunchAgents/com.synamedia.videoguardmonitor.plist
Executable: /bin/sh -c $HOME/Library/Synamedia/VideoGuardPlayer/VideoGuardMonitor/VideoGuardMonitor.bundle/Contents/Resources/launch.sh
A 2 - You can use Find Any File (FAF) do a search for "VideoGuardMonitor". Suggest running this Application from a Safe Mode.
Q 3 - No Time Machine backup - Time Machine backup not found.
A 3 - A Time Machine Backup is very useful and can be used to Revert to Previous Working macOS.
Q 4 - Unsigned files - There are unsigned software files installed that could be adware and should be reviewed.
A 4 - Should “ Certain & Specific Software “ referenced from above be installed - it will negatively impact macOS. It is suggested, to download directly from a respected ASC Contributor, the application Malwarebytes for Mac.
It is free or paid for added features.
Run the Application and it should remove the malware / adware.
Once done, restart computer and test.