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Safari can't open the file "setup.exe" because no available application can open it.
MacBook Pro 13″, macOS 12.2
Please try suggestions given in this article.
Install Windows 10 on your Mac with Boot Camp Assistant - Apple Support
Please try suggestions given in this article.
Install Windows 10 on your Mac with Boot Camp Assistant - Apple Support
That is because any .exe file is a file for Windows PCs and will not open or work on a Mac. I assume you had downloaded and attempted to install a new app. If so, go back to that web site and reselect the Mac version of the installer to download. it will have a .dmg suffix.
download file
