Slots 1 and 3 have fast (16X) slot speed to support the absolute peak performance for graphics cards. They also have cooling appropriate for hot MPX modules.
You will not change ANYTHING by moving cards to different slots. Your A-side is 100 percent full, and your B-side is 125 percent full. You are just shuffling the issue of "too much stuff" on "not enough PCI bus bandwidth" from one place to another without fixing anything..
You can not run all that stuff at rated speeds at exactly the same time. Throttling will occur if that happens.
What you need to do is decide which of your devices should be allowed to share the over-committed bandwidth, and operation of one is OK to slow the other.