"MDS" is part of Apple's Spotlight indexing feature. It is a known issue that the system logs are flooded with these messages and some well respected forum contributors have confirmed that it occurs with a clean install of macOS (no third party apps, or restore from backup). Unless you actually receive a log entry that mentions some of those "MDS" entries could not be saved because there were too many, then the only thing you can do is ignore them. Of course you can try contacting Apple Support directly and try to escalate the issue to an engineer, but you will spends lots of time and may not be successful.
You can also provide Apple with product feedback here (Apple will not respond):
You can also try contacting Apple corporate (Apple may respond):
To look for possible software issues run EtreCheck and post the report here using the "Additional Text" icon which looks like a piece of paper. If you give EtreCheck "Full Disk Access", then the report will include extra information that may provide additional clues.
FYI, normally the system logs are completely worthless for troubleshooting any macOS issues because the logs are flooded by cryptic, sanitized messages that usually appear to be programmer's debugging logs still left enabled on the released product. The only useful log these days are Kernel Panic logs and many of them can only be accessed from the Finder because the Console app actually won't display all the logs anymore (yes, that is what Apple thinks of the logs). At this point Apple should just disable system logging on released products.