Mac Studio - Focusrite Clarett 4Pre

Hi there, have you tried connecting your Scarlett interface with another cable? This (i.e. 'No Hardware Found' message) sounds a lot like a faulty connection issue, rather than anything else.

Though, of course, one should also take into account the fact that Monterey is a relatively new OS, Mac Studio is a new product, and M1 is a novel CPU. So bugs and issues are inevitable in this environment, unfortunately.

I'm just curious, would trying a purely USB-C cable instead of Thunderbolt make any difference in your case?

Really disappointing start

Indeed! Sort of, makes one wonder in what direction is Apple's Mac business going, exactly?

Anyway, I'd try to contact Focusrite's tech support on this as well, if I were you.

Mac Studio appears to be faulty (possibly damaged in transit - massive CPU spikes and the Activity Monitor is going crazy even when only basic apps are open)

This is always a possibility. And since it's brand new, you could insist on a replacement / repair via applicable warranty. Sorry you have to go through this experience. But do keep this board updated on the case, if possible.

Have you seen these two pages on the Focusrite pages?

Clarett Thunderbolt Range (2Pre, 4Pre, 8Pre and 8PreX)

Works with Monterey? YES* -

note that you may need to right-click on the Mac Thunderbolt Driver

installer to run it. If you see an error message that states that the

installer "can't be opened because Apple cannot check it for malicious

software" then please follow the instructions in this article

https://support.focusrite.com/hc/en-gb/articles/360009779240