For as many columns that you want to search I can't offhand think of a way to do it except for one or a small handful of lookups. If it was just a few columns you could concatenate them into one new column and search on that column but you won't want to concatenate columns E through AZ. The first example below uses a column to search each row then you do a lookup on that new column. The second example concatenates columns.

Formula in Table 1 cell D2 =XMATCH(Table 2::B$2;A2:C2;0)>0
fill down to complete the column
Formula in Table 2 cell B2 = XLOOKUP(TRUE,Table 1::D;Table 1::E;"na";0)
Hide column D of Table 1 when it is all set up.
Here is using concatenation:

Formula in Table 1 D2 ="-"&A2&"-"&B2&"-"&C2&"-"
fill down
Formula in Table 2 B2 =XLOOKUP(REGEX("-"&B2&"-"),Table 1::D,Table 1::E,"not found",2)
There may be better choices/combinations of formulas than the ones I used, or even a better way altogether. I don't think there is a way to do it all in one cell, though. I think it will any solution will need a column. But maybe someone else will figure out a way.