Hi, joeuu. Yes, I have an n1240U that I have been using since 10.1.5 days. If I remember correctly, the first OS X driver for it (and to Canon's credit, they were about the first company to release OS X drivers for their existing hardware) worked only as a Photoshop plug-in, but for some time now you've needrd the Toolbox even to use the PS plug-in.
I'm not at all sure that standalone scanning is possible with my n1240U, but there has been a canoscan toolbox and a need to install it for quite a while now. EDIT Yes, I checked and it looks like you should be able to scan with just the toolbox. (Of course, this may be a different version than is needed for the n1220U.)