Hi pixiegirl72,
Welcome to the Apple Community.
Re: Safari not responding : Any advice?
I'm no expert in this area, yet your post surely deserves a prompt response.
Fortunately, Apple Support have articles online that may be helpful.
Wondering if you have plenty of memory ./ storage available
(at least 50 Gb) in order for Mac OS to operate smoothly.
See used and available storage space on your Mac – Apple Support
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If you use memory-intensive software:
You might want to :View memory usage in Activity Monitor on Mac – Apple Support
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Try turning off any Ad-blockers / Safari extensions / Virus checkers (are unnecessay)
that may cause interference. Third-party (non-Apple) apps / browsers etc.sometimes cause
unusual interference, and some may become incompatible / out-of-date.
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What to do: If you can’t open a Safari window on Mac – Apple Support\
or
If Safari on Mac doesn't open a webpage or isn’t working as expected - Apple Support
and
If an app on your Mac stops responding, closes unexpectedly or won’t open – Apple Support
All the best :-)