What can I do besides change my password if my iCloud/iPhone has been hacked?

Already use two-factor.

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Why do you think your iPhone was hacked?

No, if you haven't jailbroken your iPhone, it's not possible.

To keep your Apple ID account secure, see the following Apple articles: 

If you think your Apple ID has been compromised

If you think your Apple ID has been compromised - Apple Support

See who has access to your device or accounts

See who has access to your iPhone or iPad – Apple Support (UK)

Delete suspicious content from your devices

Delete suspicious content from your devices – Apple Support (UK)

Check your Apple ID device list to see where you're signed in

Check your Apple ID device list to find where you're signed in - Apple Support

• if you see devices that don't belong to you, delete from your account.

Personal Safety User Guide

Personal Safety User Guide – Apple Support (UK)

Manage and use your Apple ID

Manage and use your Apple ID – Apple Support (UK)

Change your Apple ID password -> Change your Apple ID password - Apple Support

• Create a strong password for your Apple ID, It is best if your password consists of eight or more characters and include upper and lowercase letters, and at least one number. You can also add extra characters and punctuation marks to make your password even stronger. 
• Never provide your password, passcode, security questions, verification codes, recovery key or any other account security details to anyone else. Apple will never ask you for this information.

Then see this Apple article: What to do after you change your Apple ID or password

What to do after you change your Apple ID or password - Apple Support